IAEM 2021 – Peripheral Vasopressors

10 Nov

I had the pleasure of speaking at the IAEM 2021 Pre conference on critical care in the ED and took on the topic of peripheral pressors.

I have included a video of the talk below and some references for those interested in doing some further reading.



First 10 EM

Permpikul C, Tongyoo S, Viarasilpa T, Trainarongsakul T, Chakorn T, Udompanturak S. Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER). A Randomized Trial. Am J Respir Crit Care Med. 2019 May 1;199(9):1097-1105. doi: 10.1164/rccm.201806-1034OC. PMID: 30704260.

Reynolds PM, MacLaren R, Mueller SW, Fish DN, Kiser TH. Management of extravasation injuries: a focused evaluation of noncytotoxic medications. Pharmacotherapy. 2014 Jun;34(6):617-32. doi: 10.1002/phar.1396. Epub 2014 Jan 13. PMID: 24420913.

David V, Christou N, Etienne P, Almeida M, Roux A, Taibi A, Mathonnet M. Extravasation of Noncytotoxic Drugs. Ann Pharmacother. 2020 Aug;54(8):804-814. doi: 10.1177/1060028020903406. Epub 2020 Feb 13. PMID: 32054312.

Tian DH, Smyth C, Keijzers G, Macdonald SP, Peake S, Udy A, Delaney A. Safety of peripheral administration of vasopressor medications: A systematic review. Emerg Med Australas. 2020 Apr;32(2):220-227. doi: 10.1111/1742-6723.13406. Epub 2019 Nov 7. PMID: 31698544.

Lewis T, Merchan C, Altshuler D, Papadopoulos J. Safety of the Peripheral Administration of Vasopressor Agents. J Intensive Care Med. 2019 Jan;34(1):26-33. doi: 10.1177/0885066616686035. Epub 2017 Jan 11. PMID: 28073314.

Pancaro C, Shah N, Pasma W, Saager L, Cassidy R, van Klei W, Kooij F, Vittali D, Hollmann MW, Kheterpal S, Lirk P. Risk of Major Complications After Perioperative Norepinephrine Infusion Through Peripheral Intravenous Lines in a Multicenter Study. Anesth Analg. 2020 Oct;131(4):1060-1065. doi: 10.1213/ANE.0000000000004445. PMID: 32925324.

Tran QK, Mester G, Bzhilyanskaya V, Afridi LZ, Andhavarapu S, Alam Z, Widjaja A, Andersen B, Matta A, Pourmand A. Complication of vasopressor infusion through peripheral venous catheter: A systematic review and meta-analysis. Am J Emerg Med. 2020 Nov;38(11):2434-2443. doi: 10.1016/j.ajem.2020.09.047. Epub 2020 Sep 28. PMID: 33039229.

Shrestha N, Acharya U, Shrestha PS, Acharya SP, Karki B, Dhakal SS. Topical nitroglycerin for management of peripheral extravasation of vasopressors: a case report. Oxf Med Case Reports. 2020 Aug 10;2020(8):omaa066. doi: 10.1093/omcr/omaa066. PMID: 32793370; PMCID: PMC7416830.

Medlej K, Kazzi AA, El Hajj Chehade A, Saad Eldine M, Chami A, Bachir R, Zebian D, Abou Dagher G. Complications from Administration of Vasopressors Through Peripheral Venous Catheters: An Observational Study. J Emerg Med. 2018 Jan;54(1):47-53. doi: 10.1016/j.jemermed.2017.09.007. Epub 2017 Oct 27. PMID: 29110979.

Nguyen TT, Surrey A, Barmaan B, Miller S, Oswalt A, Evans D, Dhindsa H. Utilization and extravasation of peripheral norepinephrine in the emergency department. Am J Emerg Med. 2021 Jan;39:55-59. doi: 10.1016/j.ajem.2020.01.014. Epub 2020 Jan 8. PMID: 31959524.

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